Matias Vecino's brilliant long-range strike earned Lazio a 1-0 win at Napoli on Friday as the runaway Serie A leaders lost for only the second time in the league this season.

Manchester United's reward for getting the better of LaLiga leaders Barcelona in the Europa League playoffs is a last-16 clash with another Spanish side Real Betis, while Premier League table-toppers Arsenal will face Portuguese outfit Sporting.

Simone Inzaghi's side stay second and are three points ahead of local rivals AC Milan, who beat Monza 1-0 earlier on Saturday, but are a long way behind rampant Napoli after their 2-0 win at Sassuolo on Friday.

It looks only a matter of time before Luciano Spalletti's rampant side secure a Scudetto dreamed of by Napoli fans since the days of Diego Maradona

A 33-year wait for the league crown looks closer to ending for Napoli

Milan last won a game over a month ago

Italian media report that Galatasaray offered Roma 16.5 million euros ($17.7 million) with add-ons of up to 13 million euros to take Zaniolo off their hands.

AC Milan's crisis threatens to deepen as the champions head into Sunday's derby with Inter, miles off the Serie A title pace and in a battle to reach next year's Champions League.

Juventus will face Inter Milan in the last four of the Italian Cup after beating Lazio 1-0 in Thursday's final quarter-final tie.

Serie A title fever is sweeping Naples as the football-mad city hopes that rampant Napoli will end more than three decades of waiting to be crowned kings of Italy.

Milan prosecutors are looking into last year's 1.2 billion euro ($1.3 billion) sale of AC Milan to U.S. private equity fund RedBird Capital from U.S. fund Elliott, a judicial source said on Thursday.

Lazio shot into Serie A's Champions League places on Tuesday after hammering AC Milan 4-0 to leave the champions' title defence hanging by a thread.

Premier League leaders Arsenal signed Poland defender Jakub Kiwior from Italian side Spezia in a deal worth a reported £12 million ($27 million) on Monday.

Napoli must seize their "unprecedented opportunity" to win the Scudetto after reaching 50 points at the halfway mark of the Serie A season by beating Salernitana, said Luciano Spalletti.

 Juventus manager Massimiliano Allegri has urged his team to "do their duty" on the pitch after the Serie A side were deducted 15 points by an Italian soccer court on Friday, leaving them marooned in mid-table.

Barcelona coach Xavi Hernandez said Saturday that he is in "a state of shock" after Dani Alves's arrest on sexual assault allegations.

Juventus JUVE.MI have been deducted 15 points for the current season by an Italian soccer court investigating the club's transfer dealings, leaving the country's most successful team marooned in mid-table.

Davide Nicola has been brought back as coach of Salernitana just two days after being sacked, the Serie A club confirmed to AFP on Wednesday.

Outgoing Juventus Chairman Andrea Agnelli said on Wednesday that he would also quit his roles on the boards of carmaker Stellantis STLA.MI and Exor <EXOR.AS>, the Agnelli family's holding company.

A new board at Italian soccer club Juventus JUVE.MI will be appointed this week and plunged straight into its accounting scandal, with a hearing on Friday before sporting authorities on its transfer dealings.